Ulcerative Colitis

Comprehensive Care by Dr. Kushan Kaushik Sengupta – Renowned Consultant Gastroenterologist in Kolkata

Ulcerative Colitis (UC) is a chronic type of Inflammatory Bowel Disease (IBD) that causes long-standing inflammation and ulcer formation in the lining of the large intestine (colon) and rectum. It typically develops gradually and is characterized by alternating periods of flare-ups and remission. If untreated, Ulcerative Colitis can severely impact daily life and may lead to serious complications.

Dr. Kushan Kaushik Sengupta, a highly experienced Consultant Gastroenterologist, Hepatologist & Interventional Endoscopist, is widely regarded as one of the best Gastroenterologists in Kolkata for managing complex digestive disorders such as Ulcerative Colitis. His expertise in advanced diagnostics, targeted treatments, and long-term disease management ensures patients receive personalized, effective, and compassionate care.

Understanding Ulcerative Colitis

Ulcerative Colitis occurs when the immune system mistakenly attacks the colon’s lining, leading to continuous inflammation and ulceration. While the exact cause remains unknown, several contributing factors have been identified:

  • Genetic predisposition

  • Immune system dysfunction

  • Imbalance of gut microbiota

  • Lifestyle and environmental factors

  • Stress and dietary triggers (worsening flare-ups)

Symptoms vary depending on the extent and severity of inflammation. Typical signs include:

  • Persistent diarrhea (often with blood or mucus)

  • Abdominal cramping and pain

  • Urgency to pass stool

  • Rectal bleeding

  • Weight loss and loss of appetite

  • Fatigue and weakness

  • Fever during flare-ups

  • Anemia due to chronic blood loss

  • Dehydration and electrolyte imbalance

  • In severe cases, sudden severe abdominal pain or bloating

Early medical evaluation is essential to avoid complications such as severe bleeding, toxic megacolon, or colorectal cancer.

Common Signs & Symptoms

Diagnostic Procedures

Dr. Kushan Kaushik Sengupta follows a comprehensive and systematic diagnostic approach to confirm Ulcerative Colitis and assess disease severity.

Diagnostic evaluations include:

Detailed Clinical History & Physical Examination

Assessment of symptom duration, pattern, triggers, and overall health.

Blood Tests

To detect anemia, infection, or signs of inflammation (CRP, ESR).

Stool Tests

Calprotectin and other markers to differentiate UC from infections or other forms of IBD.

Colonoscopy with Biopsy

The gold standard to visualize inflammation, ulcers, and obtain tissue samples for accurate diagnosis.

Sigmoidoscopy

Useful for evaluating inflammation limited to the lower colon.

CT / MRI Enterography

Advanced imaging to assess complications such as severe inflammation, perforation, or toxic megacolon.

With precise evaluation and staging, Dr. Sengupta ensures each patient receives a targeted and evidence-based treatment plan.

Treatment Options for Ulcerative Colitis

While Ulcerative Colitis cannot be completely cured, modern treatments make it possible to manage symptoms, achieve remission, and improve long-term outcomes.

Medical Management

Aminosalicylates (5-ASA):
First-line treatment to reduce inflammation in mild to moderate UC.

Corticosteroids:
Used for short-term control during acute flare-ups.

Immunosuppressants:
Medications like Azathioprine or Cyclosporine to suppress immune overactivity.

Biologic Therapy:
Advanced targeted drugs (Anti-TNF agents, Anti-integrin therapy, JAK inhibitors) for moderate to severe UC.

Antibiotics:
Prescribed when infections or complications are suspected.

Nutritional & Lifestyle Therapy

  • Personalized diet plans to avoid trigger foods

  • Management of nutritional deficiencies

  • Guidance on hydration, stress control, and gut-friendly habits

Endoscopic & Interventional Care

As a skilled Interventional Endoscopist, Dr. Sengupta performs advanced procedures to manage complications such as strictures, bleeding, or severe inflammation.

Surgical Management

Surgery is considered when medical treatment fails or complications arise (such as perforation, severe bleeding, or cancer risk).
Dr. Sengupta works closely with expert GI surgeons to ensure safe, coordinated, and seamless care.

Why Choose Dr. Kushan Kaushik Sengupta for Ulcerative Colitis Care in Kolkata?

  • Renowned Consultant Gastroenterologist, Hepatologist & Interventional Endoscopist

  • Highly experienced in managing complex IBD cases, including Ulcerative Colitis and Crohn’s Disease

  • Expert in advanced diagnostics such as colonoscopy, capsule endoscopy & imaging-based evaluations

  • Comprehensive treatment combining medicine, endoscopy, nutrition, and long-term monitoring

  • Patient-first care philosophy with clear communication and compassionate support

  • Widely recognized as one of the best Gastroenterologists in Kolkata for digestive and liver disorders

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